Research Interest: Viral pathogenesis; Vaccine; Genome expression patterns; Microarray; Next Generation Sequencing; Animal diseases; Protein-protein interactions; Viral-host cell interactions; African swine fever Virus; Classical swine fever virus; Foot-and-Mouth Disease Virus

Research Interest: Foodborne pathogens, food of animal origin, residues of veterinary drugs, farmed fish, chemical contaminants,Foodborne pathogens in food of animal origin

Residues of veterinary drugs in farmed fish 

Chemical contaminants in food of animal origin

Research Interest: Veterinary and Molecular Microbiology

Research Interest: Embryos, Oocytes, IVM, Embryo Transfer, Embryo Culture, Assisted Reproductive Technology, Reproductive Biology

Dr. Xiangyang Miao is a Professor at Institute of Animal Sciences, Chinese Academy of Agricultural Sciences in Beijing. He performed his doctoral studies in Biochemistry and Molecular Biology at College of Biological Sciences, China Agricultural University. He also worked as a visiting professor at University of Guelph, Canada, Harvard University, University of California, Davis, and University of Maryland, USA. He is a principal investigator and academic leader which successively lead more than 30 projects. His research area is molecular and developmental biology, functional genomics, and molecular breeding. His research interests currently focus on developmental biology, genomics, epigenomics, high throughput sequencing, bioinformatics and molecular biology. He is an evaluation expert in National Natural Science Foundation of China, The National Scholarship Fund, Beijing Natural Science Foundation, Beijing Municipal Science and Technology Commission, Beijing Science and Technology Award, Beijing Senior Professional Title, The National Key Research and Development Program of China, China Academic Degrees and Graduate Education Development Center, European Commission Horizon, Times Higher Education World University Rankings, China National Knowledge Infrastructure (CNKI), Anhui Science and Technology Project, Jiangsu Science and Technology Consultation etc. He is an associate Editor for Frontiers in Endocrinology, Frontiers in Physiology, Frontiers in Genetics, Frontiers in Veterinary Science and BMC Veterinary Research, etc. He is an outstanding expert of Chinese Academy of Agricultural Sciences. He has published more than 150 peer-reviewed papers, including papers in Cellular and Molecular Life Sciences, Molecular and Cellular Endocrinology, Reproduction, Scientific Reports, Frontiers in Physiology, Gene, Reproductive Biology and Endocrinology, Animal Reproduction Science etc. Prof. Miao has authored or co-authored English monograph and multiple Chinese volumes. He has also obtained numerous patents, both domestically and internationally. He has also applied for many national invention patents.

Research Interest: Molecular and developmental biology; Functional genomics; Epigenetics; High throughput genomics; Bioinformatics; Molecular breeding.

Publications List:

1. Tianyi Liu, Hui Feng,Salsabeel Yousuf, Lingli Xie, Xiangyang Miao. Functional analysis of diferentially expressed circular RNAs in sheep subcutaneous fat. BMC Genomics, (2023) 24: 591.
   
2. Salsabeel Yousuf, Waqar Afzal Malik, Hui Feng, Tianyi Liu, Lingli Xie, Xiangyang Miao. Genome wide identifcation and characterization of fertility associated novel CircRNAs as ceRNA reveal their regulatory roles in sheep fecundity. Journal of Ovarian Research, 2023, 16: 115.
3. Hui Feng, Tianyi Liu, Salsabeel Yousuf, Xiuxiu Zhang, Wanlong Huang, Ai Li, Lingli Xie and Xiangyang Miao. Identification and analysis of lncRNA, miRNA and mRNA related to subcutaneous and intramuscular fat in Laiwu pigs. Frontiers in Endocrinology, 2023, 13: 1081460.
4. Lingli Xie, Xiangyang Miao *, Qingmiao Luo, Huijing Zhao, Xiaoyu Qin. Impact of FecB mutation on ovarian DNA methylome in Small-Tail Han sheep. Genes. 2023, 14(1): 203
5. Xiuxiu Zhang, Wanlong Huang, Yuntao Guo and Xiangyang Miao *. Integrative analysis of miRNAs involved in fat deposition in different pig breeds. Genes. 2023, 14(1): 94
6. Salsabeel Yousuf, Ai Li, Hui Feng, Tianyi Liu, Wanlong Huang, Xiuxiu Zhang, Lingli Xie, Xiangyang Miao.Genome-wide expression profiling and networking reveals an imperative role of IMF-associated novel circRNAs as ceRNA in pigs. Cells, 2022, 11: 2638.
7. Tianyi Liu Hui Feng, Salsabeel Yousuf, Lingli Xie, Xiangyang Miao. Genome-wide analysis of microRNAs identifies the lipid metabolism pathway to be a defining factor in adipose tissue from different sheep. Frontiers in Veterinary Science, 9: 938311.
8. Tianyi Liu Hui Feng, Salsabeel Yousuf, Lingli Xie, Xiangyang Miao. Differential regulation of mRNAs and lncRNAs related to lipid metabolism in Duolang and Small Tail Han Sheep. Scientific Reports, 12: 11157
9. Hui Feng, Tianyi Liu, Salsabeel Yousuf, Xiuxiu Zhang, Wanlong Huang, Ai Li, Lingli Xie, Xiangyang Miao. Identification of potential miRNA-mRNA regulatory network and the key miRNAs in intramuscular and subcutaneous adipose. Frontiers in Veterinary Science, 2022, 9: 976603.
10. Hui Feng, Salsabeel Yousuf, Tianyi Liu, Xiuxiu Zhang, Wanlong Huang, Ai Li, Lingli Xie, Xiangyang Miao. The comprehensive detection of miRNA and circRNA in the regulation of intramuscular and subcutaneous adipose tissue of Laiwu pig. Scientific Reports, 2022, 12: 16542.
11. Samina Shabbir, Prerona Boruah, Lingli Xie, Muhammad Fakhar-e-Alam Kulyar , Mohsin Nawaz, SalsabeelYousuf, Tianyi Liu, Farhat Jabeen, Xiangyang Miao*. Genome-wide transcriptome profiling uncovers differential miRNAs and lncRNAs in ovaries of Hu sheep at different developmental stages. Scientifc Reports, 2021, 11: 5865.
12. Xiangyang Miao∗ Qingmiao Luo Lingli Xie Huijing Zhao Xiaoyu Qin. Comparative DNA methylome analysis of estrus ewes reveals the complex regulatory pathways of sheep fecundity. Reproductive Biology and Endocrinology, 2020, 18: 77.
13. Wanlong Huang, Xiuxiu Zhang, Ai Li, Lingli Xie, Xiangyang Miao*. Genome-wide analysis of mRNAs and lncRNAs of intramuscular fat related to lipid metabolism in two pig breeds. Cellular Physiology and Biochemistry, 2018, 50: 2406–2422.
14. Ai Li, Wanlong Huang, Xiuxiu Zhang, Lingli Xie, Xiangyang Miao*. Identification and characterization of circRNAs of two pig breeds as a new biomarker in metabolism-related diseases. Cellular Physiology and Biochemistry, 2018, 47: 2458
15. Xiangyang Miao, Qingmiao Luo, Huijing Zhao, Xiaoyu Qin. Ovarian transcriptomic analysis reveals the alternative splicing events associated with fecundity in different sheep breeds. Animal Reproduction Science, 2018, 198: 177–183.
16. Wanlong Huang, Xiuxiu Zhang, Ai Li, Lingli Xie, Xiangyang Miao*. Differential regulation of mRNAs and lncRNAs related to lipid metabolism in two pig breeds. Oncotarget, 2017, 8: 87539-87553.
17. Wanlong Huang, Yuntao Guo, Weihua Du, Xiuxiu Zhang, Ai Li, Xiangyang Miao*. Global transcriptome analysis identifies differentially expressed genes related to lipid metabolism in Wagyu and Holstein cattle. Scientific Reports, 2017, 7, 5278.
18. Yuntao Guo, Xiuxiu Zhang, Wanlong Huang, Xiangyang Miao*. Identification and characterization of differentially expressed miRNAs in subcutaneous adipose between Wagyu and Holstein cattle. Scientific Reports, 2017, 7: 44026
19. Xiangyang Miao, Qingmiao Luo, Huijing Zhao, Xiaoyu Qin. An integrated analysis of miRNAs and methylated genes encoding mRNAs and lncRNAs in sheep breeds with different fecundity. Frontiers in Physiology, 2017, 8: 1049.
20. Xiangyang Miao Recent advances in understanding the role of miRNAs in exosomes and their therapeutic potential. Journal of Integrative Agriculture, 2017, 16(4), 753-761.
21. Xiangyang Miao, Qingmiao Luo, Huijing Zhao & Xiaoyu Qin. Co-expression analysis and identification of fecundity-related long non-coding RNAs in sheep ovaries. Scientific Reports, 2016, 6, 39398.
22. Xiangyang Miao, Qingmiao Luo, Huijing Zhao, Xiaoyu Qin. Genome-wide analysis of miRNAs in the ovaries of Jining Grey and Laiwu Black goats to explore the regulation of fecundity. Scientific Reports, 2016, 6, 37983.
23. Xiangyang Miao, Qingmiao Luo, Huijing Zhao & Xiaoyu Qin. Ovarian transcriptomic study reveals the differential regulation of miRNAs and lncRNAs related to fecundity in different sheep. Scientific Reports, 2016, 6, 35299.
24. Xiangyang Miao, Qingmiao Luo, Xiaoyu Qin. Genome-wide transcriptome analysis in the ovaries of two goats identifies differentially expressed genes related to fecundity. Gene, 2016, 582, 69-76.
25. Xiangyang Miao, Qingmiao Luo, Huijing Zhao, Xiaoyu Qin. Ovarian proteomic study reveals the possible molecular mechanism for hyperprolificacy of Small Tail Han sheep. Scientific Reports, 2016, 6, 27606.
26. Xiangyang Miao, Qingmiao Luo, Xiaoyu Qin. Genome-wide analysis reveals the differential regulations of mRNAs and miRNAs in Dorset and Small Tail Han sheep muscles. Gene, 2015, 562(2): 188–196.
27. Xiangyang Miao, Qingmiao Luo, Xiaoyu Qin, Yuntao Guo, Huijing Zhao. Genome-wide mRNA-seq profiling reveals predominant downregulation of lipid metabolic processes in adipose tissues of Small Tail Han than Dorset sheep. Biochemical and Biophysical Research Communications 2015, 467: 413-420.
28. Xiangyang Miao, Qingmiao Luo, Xiaoyu Qin, Yuntao Guo. Genome-wide analysis of microRNAs identifies the lipid metabolism pathway to be a defining factor in adipose tissue from different sheep. Scientific Reports, 2015, 5:18470
29. Xiangyang Miao, Qingmiao Luo, Xiaoyu Qin. Genome-wide transcriptome analysis of mRNAs and microRNAs in Dorset and Small Tail Han sheep to explore the regulation of fecundity. Molecular and Cellular Endocrinology, 2015. 402: 32–42.
30. Xiangyang Miao. Recent advances in the development of new transgenic animal technology. Cellular and Molecular Life Sciences, 2013, 70(5): 815-828.
31. Xiangyang Miao, Qingmiao Luo. Genome-wide transcriptome analysis between Small-tail Han sheep and the surabaya fur sheep using high-throughput RNA sequencing. Reproduction, 2013, 145: 587-596.

Research Interest: Quantitative microscopy and stereology,Histology and developmental biology of microvessels,Human and veterinary anatomy, histology and embryology,Biocompatibility and healing supported by tissue scaffolds and biomaterials,blood vessels; quantitative histology; stereology; tissue healing